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The Arkansas Supreme Court has rejected requests for stays of execution from two inmates set to die in the nation's first double execution since 2000.

Jack Jones Jr. and Marcel Williams had asked the state's highest court to stop their executions, which are set for Monday night. Arkansas is trying to use a sedative that expires at the end of the month, and if the men don't receive lethal injections as scheduled their executions will be off indefinitely.

The state has said it has no new source for midazolam.

A federal appeals court has rejected an Arkansas inmate's request for a stay of execution for the rape and killing of a woman more than two decades ago.

Jack Jones Jr. says his lethal injection could be cruel and unusual because he is diabetic and overweight. The 8th U.S. Circuit Court of Appeals denied his request Monday, hours before his scheduled execution.

Jones was convicted of raping and strangling Mary Phillips at a Bald Knob accounting office on June 6, 1995.

A federal judge says she won't block two inmates from being executed next week in Arkansas, rejecting the men's claims that their poor health could make the lethal injections especially painful.

U.S. District Judge Kristine Baker denied requests to stop the executions for Jack Jones and Marcel Williams, both of which are scheduled for Monday night.

Williams argues that his obesity and diabetes could make the lethal injections too painful. Jones argues that his diabetes, high blood pressure and other conditions could cause him to suffer an "extended and painful death."

Arkansas has executed an inmate for the first time in nearly a dozen years as part of its plan to execute several inmates before a drug expires April 30, despite court rulings that have already spared three men.

Ledell Lee was pronounced dead at 11:56 p.m. Thursday. The 51-year-old Lee was given the death penalty for the 1993 death of his neighbor Debra Reese, whom Lee struck 36 times with a tire tool.

The Arkansas Supreme Court is allowing the state to use a lethal injection drug in upcoming executions, despite a supplier's complaint that it was sold to the state to be used only for inmates' medical care.

Justices on Thursday lifted a judge's order preventing the state from using its supply of vecuronium bromide, one of three drugs used in Arkansas' lethal injection protocol. McKesson Corp., a medical supply company, said the state misleadingly bought the drug and that it wasn't intended for executions.

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